STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pla2g4cPLA2c domain-containing protein. (581 aa)    
Predicted Functional Partners:
LOC103129695
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.940
LOC103151912
Cytochrome P450, family 4, subfamily F, polypeptide 3; Belongs to the cytochrome P450 family.
     
 0.934
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
  0.931
ENSPFOP00000008202
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
  0.931
alox5
Arachidonate 5-lipoxygenase a.
     
 0.925
ENSPFOP00000008208
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.925
LOC103148853
Arachidonate 12-lipoxygenase.
     
 0.925
LOC103133329
Uncharacterized protein.
   
 
 0.925
enpp6
Ectonucleotide pyrophosphatase/phosphodiesterase 6.
   
 
  0.924
pla2g7
Platelet-activating factor acetylhydrolase.
     
 0.919
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.