STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000022408Ig-like domain-containing protein. (124 aa)    
Predicted Functional Partners:
LOC103140402
Mitogen-activated protein kinase kinase kinase 22.
    
  0.624
ENSPFOP00000014096
Mitogen-activated protein kinase kinase kinase 3.
    
  0.624
ENSPFOP00000017888
Mitogen-activated protein kinase kinase kinase 2.
    
  0.624
ENSPFOP00000016176
Ig-like domain-containing protein.
    
  0.621
ENSPFOP00000016490
Ig-like domain-containing protein.
    
  0.621
ENSPFOP00000016954
Ig-like domain-containing protein.
    
  0.621
ENSPFOP00000002923
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
    
  0.610
masp1
Mannan-binding lectin serine peptidase 1; Belongs to the peptidase S1 family.
    
  0.594
ENSPFOP00000013864
Complement component 1, r subcomponent; Belongs to the peptidase S1 family.
    
  0.594
ENSPFOP00000025082
Uncharacterized protein; Belongs to the peptidase S1 family.
    
  0.594
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.