node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSPFOP00000001436 | ENSPFOP00000011594 | ENSPFOP00000001436 | ENSPFOP00000011594 | SAS-6 centriolar assembly protein. | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | 0.903 |
ENSPFOP00000001436 | ENSPFOP00000012019 | ENSPFOP00000001436 | ENSPFOP00000012019 | SAS-6 centriolar assembly protein. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.893 |
ENSPFOP00000001436 | ENSPFOP00000024133 | ENSPFOP00000001436 | ENSPFOP00000024133 | SAS-6 centriolar assembly protein. | Uncharacterized protein. | 0.861 |
ENSPFOP00000001436 | pola1 | ENSPFOP00000001436 | ENSPFOP00000003557 | SAS-6 centriolar assembly protein. | DNA polymerase. | 0.871 |
ENSPFOP00000001436 | pola2 | ENSPFOP00000001436 | ENSPFOP00000011202 | SAS-6 centriolar assembly protein. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.878 |
ENSPFOP00000001436 | ten1 | ENSPFOP00000001436 | ENSPFOP00000012314 | SAS-6 centriolar assembly protein. | TEN1 subunit of CST complex. | 0.859 |
ENSPFOP00000009451 | ENSPFOP00000011594 | ENSPFOP00000009451 | ENSPFOP00000011594 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | 0.971 |
ENSPFOP00000009451 | ENSPFOP00000012019 | ENSPFOP00000009451 | ENSPFOP00000012019 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.973 |
ENSPFOP00000009451 | ENSPFOP00000024133 | ENSPFOP00000009451 | ENSPFOP00000024133 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. | Uncharacterized protein. | 0.995 |
ENSPFOP00000009451 | pola1 | ENSPFOP00000009451 | ENSPFOP00000003557 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. | DNA polymerase. | 0.976 |
ENSPFOP00000009451 | pola2 | ENSPFOP00000009451 | ENSPFOP00000011202 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.962 |
ENSPFOP00000009451 | ten1 | ENSPFOP00000009451 | ENSPFOP00000012314 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. | TEN1 subunit of CST complex. | 0.998 |
ENSPFOP00000011594 | ENSPFOP00000001436 | ENSPFOP00000011594 | ENSPFOP00000001436 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | SAS-6 centriolar assembly protein. | 0.903 |
ENSPFOP00000011594 | ENSPFOP00000009451 | ENSPFOP00000011594 | ENSPFOP00000009451 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. | 0.971 |
ENSPFOP00000011594 | ENSPFOP00000012019 | ENSPFOP00000011594 | ENSPFOP00000012019 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.999 |
ENSPFOP00000011594 | ENSPFOP00000024133 | ENSPFOP00000011594 | ENSPFOP00000024133 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | Uncharacterized protein. | 0.940 |
ENSPFOP00000011594 | LOC103129860 | ENSPFOP00000011594 | ENSPFOP00000000782 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | 0.913 |
ENSPFOP00000011594 | LOC103135288 | ENSPFOP00000011594 | ENSPFOP00000009792 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | 0.913 |
ENSPFOP00000011594 | LOC103142380 | ENSPFOP00000011594 | ENSPFOP00000004994 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | RPA_C domain-containing protein. | 0.913 |
ENSPFOP00000011594 | pola1 | ENSPFOP00000011594 | ENSPFOP00000003557 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | DNA polymerase. | 0.999 |