node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSPFOP00000004136 | ENSPFOP00000004469 | ENSPFOP00000004136 | ENSPFOP00000004469 | NOP58 ribonucleoprotein homolog (yeast). | Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. | 0.707 |
ENSPFOP00000004136 | ENSPFOP00000014516 | ENSPFOP00000004136 | ENSPFOP00000014516 | NOP58 ribonucleoprotein homolog (yeast). | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.491 |
ENSPFOP00000004136 | LOC103133919 | ENSPFOP00000004136 | ENSPFOP00000019288 | NOP58 ribonucleoprotein homolog (yeast). | Nucleophosmin 1a. | 0.698 |
ENSPFOP00000004136 | LOC103137300 | ENSPFOP00000004136 | ENSPFOP00000018460 | NOP58 ribonucleoprotein homolog (yeast). | Nucleophosmin 1b. | 0.698 |
ENSPFOP00000004136 | LOC103148870 | ENSPFOP00000004136 | ENSPFOP00000012514 | NOP58 ribonucleoprotein homolog (yeast). | Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family. | 0.707 |
ENSPFOP00000004136 | eif3a | ENSPFOP00000004136 | ENSPFOP00000007800 | NOP58 ribonucleoprotein homolog (yeast). | Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 0.772 |
ENSPFOP00000004136 | ncl | ENSPFOP00000004136 | ENSPFOP00000025564 | NOP58 ribonucleoprotein homolog (yeast). | Nucleolin. | 0.881 |
ENSPFOP00000004136 | pan2 | ENSPFOP00000004136 | ENSPFOP00000008885 | NOP58 ribonucleoprotein homolog (yeast). | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] | 0.445 |
ENSPFOP00000004469 | ENSPFOP00000004136 | ENSPFOP00000004469 | ENSPFOP00000004136 | Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. | NOP58 ribonucleoprotein homolog (yeast). | 0.707 |
ENSPFOP00000004469 | ENSPFOP00000014516 | ENSPFOP00000004469 | ENSPFOP00000014516 | Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.773 |
ENSPFOP00000004469 | LOC103148870 | ENSPFOP00000004469 | ENSPFOP00000012514 | Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. | Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family. | 0.922 |
ENSPFOP00000004469 | NCBP1 | ENSPFOP00000004469 | ENSPFOP00000004402 | Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. | Nuclear cap binding protein subunit 1. | 0.781 |
ENSPFOP00000004469 | eif3a | ENSPFOP00000004469 | ENSPFOP00000007800 | Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. | Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 0.911 |
ENSPFOP00000004469 | ncl | ENSPFOP00000004469 | ENSPFOP00000025564 | Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. | Nucleolin. | 0.849 |
ENSPFOP00000004469 | pan2 | ENSPFOP00000004469 | ENSPFOP00000008885 | Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] | 0.746 |
ENSPFOP00000004469 | pan3 | ENSPFOP00000004469 | ENSPFOP00000007548 | Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] | 0.653 |
ENSPFOP00000014516 | ENSPFOP00000004136 | ENSPFOP00000014516 | ENSPFOP00000004136 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | NOP58 ribonucleoprotein homolog (yeast). | 0.491 |
ENSPFOP00000014516 | ENSPFOP00000004469 | ENSPFOP00000014516 | ENSPFOP00000004469 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. | 0.773 |
ENSPFOP00000014516 | LOC103148870 | ENSPFOP00000014516 | ENSPFOP00000012514 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family. | 0.773 |
ENSPFOP00000014516 | NCBP1 | ENSPFOP00000014516 | ENSPFOP00000004402 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Nuclear cap binding protein subunit 1. | 0.999 |