| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC106952614 | LOC106953123 | ENSPLAP00000020233 | ENSPLAP00000003294 | SIN3 transcription regulator family member Ab. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.878 |
| LOC106952614 | LOC106958579 | ENSPLAP00000020233 | ENSPLAP00000000029 | SIN3 transcription regulator family member Ab. | RE1-silencing transcription factor. | 0.897 |
| LOC106952614 | hdac8 | ENSPLAP00000020233 | ENSPLAP00000002617 | SIN3 transcription regulator family member Ab. | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.866 |
| LOC106952614 | kdm1a | ENSPLAP00000020233 | ENSPLAP00000017056 | SIN3 transcription regulator family member Ab. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.460 |
| LOC106952614 | rcor1 | ENSPLAP00000020233 | ENSPLAP00000024527 | SIN3 transcription regulator family member Ab. | REST corepressor 1. | 0.662 |
| LOC106952614 | rcor2 | ENSPLAP00000020233 | ENSPLAP00000009648 | SIN3 transcription regulator family member Ab. | REST corepressor 2. | 0.647 |
| LOC106952614 | rcor3 | ENSPLAP00000020233 | ENSPLAP00000022409 | SIN3 transcription regulator family member Ab. | REST corepressor 3. | 0.647 |
| LOC106953123 | LOC106952614 | ENSPLAP00000003294 | ENSPLAP00000020233 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | SIN3 transcription regulator family member Ab. | 0.878 |
| LOC106953123 | LOC106958579 | ENSPLAP00000003294 | ENSPLAP00000000029 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | RE1-silencing transcription factor. | 0.767 |
| LOC106953123 | htt | ENSPLAP00000003294 | ENSPLAP00000005791 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Huntingtin. | 0.412 |
| LOC106953123 | kdm1a | ENSPLAP00000003294 | ENSPLAP00000017056 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.930 |
| LOC106953123 | rcor1 | ENSPLAP00000003294 | ENSPLAP00000024527 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | REST corepressor 1. | 0.886 |
| LOC106953123 | rcor2 | ENSPLAP00000003294 | ENSPLAP00000009648 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | REST corepressor 2. | 0.819 |
| LOC106953123 | rcor3 | ENSPLAP00000003294 | ENSPLAP00000022409 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | REST corepressor 3. | 0.819 |
| LOC106953123 | sin3a | ENSPLAP00000003294 | ENSPLAP00000019835 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | SIN3 transcription regulator family member Aa. | 0.878 |
| LOC106953123 | sin3b | ENSPLAP00000003294 | ENSPLAP00000030175 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | SIN3 transcription regulator family member B. | 0.896 |
| LOC106958579 | LOC106952614 | ENSPLAP00000000029 | ENSPLAP00000020233 | RE1-silencing transcription factor. | SIN3 transcription regulator family member Ab. | 0.897 |
| LOC106958579 | LOC106953123 | ENSPLAP00000000029 | ENSPLAP00000003294 | RE1-silencing transcription factor. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.767 |
| LOC106958579 | hdac8 | ENSPLAP00000000029 | ENSPLAP00000002617 | RE1-silencing transcription factor. | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.767 |
| LOC106958579 | htt | ENSPLAP00000000029 | ENSPLAP00000005791 | RE1-silencing transcription factor. | Huntingtin. | 0.921 |