Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
polr2mRNA polymerase II subunit M. (332 aa)    
Predicted Functional Partners:
polr2c
Polymerase (RNA) II (DNA directed) polypeptide C.
    
 
 0.987
polr2g
Polymerase (RNA) II (DNA directed) polypeptide G-like.
    
 
 0.985
polr2l
Polymerase (RNA) II (DNA directed) polypeptide L.
    
 
 0.981
polr2d
Polymerase (RNA) II (DNA directed) polypeptide D.
    
 
 0.981
rpap2
RNA polymerase II associated protein 2.
    
 
 0.979
rpap1
RNA polymerase II associated protein 1.
    
 
 0.979
polr2b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.978
gpn1
GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
   
 
 0.976
supt6h
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
    
 
 0.975
POLR2E
RNA polymerase II subunit E.
    
 
 0.975
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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