Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
setUncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (266 aa)    
Predicted Functional Partners:
LOC106952753
Prothymosin alpha b.
   
 
 0.852
anp32a
Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A.
   
 0.844
LOC106956331
Histone H2A; Belongs to the histone H2A family.
   
 
 0.843
H2AZ1
Histone H2A; Belongs to the histone H2A family.
   
 
 0.843
LOC106939241
Uncharacterized protein.
   
 0.838
anp32e
Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E.
   
 0.838
anp32b
Acidic (leucine-rich) nuclear phosphoprotein 32 family, member B.
   
 0.838
LOC106935115
Uncharacterized protein.
   
 0.838
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.709
ptges3
Prostaglandin E synthase 3b (cytosolic).
   
    0.700
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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