Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
irf8Interferon regulatory factor 8. (422 aa)    
Predicted Functional Partners:
LOC106946993
Spi-1 proto-oncogene b.
   
 
 0.850
LOC106942585
ETS domain-containing protein.
   
 
 0.850
LOC106947732
ETS domain-containing protein.
   
 
 0.724
il10
Interleukin 10.
    
 
 0.712
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.676
LOC106950556
Interferon regulatory factor.
   
 0.672
LOC106950871
Signal transducer and activator of transcription.
    
 0.636
LOC106960967
Protein phosphatase 2, regulatory subunit A, beta b.
    
  0.633
atp5f1b
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.611
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.595
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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