Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ebpEBP cholestenol delta-isomerase. (229 aa)    
Predicted Functional Partners:
sc5d
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 
 0.991
dhcr24
24-dehydrocholesterol reductase.
   
 0.983
tm7sf2
Transmembrane 7 superfamily member 2.
   
 
 0.970
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 
 0.965
LOC106949687
Hydroxysteroid (17-beta) dehydrogenase 7.
   
 
 0.965
nsdhl
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
  
 0.819
atp6v0d1
V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.
    
 
 0.813
dhcr7
7-dehydrocholesterol reductase.
   
  
 0.811
atp6v1f
V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
   
 
 0.798
ENSPLAP00000003701
Wnt ligand secretion mediator.
    
   0.766
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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