STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxo21F-box protein 21. (637 aa)    
Predicted Functional Partners:
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.944
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.908
LOC106937213
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.837
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.837
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.812
rps27a
Ribosomal protein S27a.
   
  0.785
LOC106934764
NEDD8 ubiquitin like modifier.
    
 0.725
LOC106944743
NEDD8 ubiquitin like modifier.
    
 0.725
trip12
Thyroid hormone receptor interactor 12.
    
 0.696
nae1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
    
 0.693
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.