Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
srbd1S1 motif domain-containing protein. (1002 aa)    
Predicted Functional Partners:
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.893
IWS1
Interacts with SUPT6H, CTD assembly factor 1.
   
 0.892
supt5h
Transcription elongation factor SPT5.
   
 0.840
supt4h1
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.830
POLR2E
RNA polymerase II subunit E.
    
 0.811
cdc73
Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae).
   
 0.808
polr2d
Polymerase (RNA) II (DNA directed) polypeptide D.
    
 0.792
polr2g
Polymerase (RNA) II (DNA directed) polypeptide G-like.
    
 0.789
ssrp1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.783
ENSPLAP00000012395
POB3_N domain-containing protein.
   
 0.783
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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