STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106953690Mitochondrial E3 ubiquitin protein ligase 1a. (357 aa)    
Predicted Functional Partners:
usp30
Ubiquitin carboxyl-terminal hydrolase.
     
 0.771
ubxn7
UBX domain protein 7.
    
  0.746
tmem115
Transmembrane protein 115.
   
    0.736
tomm20
Translocase of outer mitochondrial membrane 20b.
     
 0.686
tomm70
Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae).
     
 0.686
rps27a
Ribosomal protein S27a.
    
  0.674
fkbp8
Peptidylprolyl isomerase.
     
 0.651
LOC106957958
COMM domain containing 5.
   
 
  0.621
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
   0.613
ccdc22
Coiled-coil domain containing 22.
   
 
  0.592
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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