Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC106953297Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (300 aa)    
Predicted Functional Partners:
rb1
Retinoblastoma 1.
   
 0.965
LOC106955228
Retinoblastoma-like 2 (p130).
   
 0.961
rbl1
Retinoblastoma-like 1 (p107).
   
 0.961
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.956
ccnd1
Cyclin D1; Belongs to the cyclin family.
   
 0.956
ENSPLAP00000008165
Cyclin Dx.
   
 0.954
LOC106956175
Cyclin D2, b; Belongs to the cyclin family.
   
 0.954
LOC106936725
Cyclin Dx; Belongs to the cyclin family.
   
 0.954
ccnd3
Cyclin D3; Belongs to the cyclin family.
   
 0.954
LOC106953382
Cyclin D2, a; Belongs to the cyclin family.
   
 0.954
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: low (32%) [HD]