PLEKHG1 protein (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PLEKHG1

Pleckstrin homology and RhoGEF domain containing G1. (1516 aa)

Predicted Functional Partners:

yap1

0.636

LOC106941957

0.596

CDC42

0.559

LOC106964683

0.559

fermt2

0.541

fermt1

0.541

LOC106960410

0.540

ENSPLAP00000025216

0.540

ENSPLAP00000025295

0.540

LOC106951125

0.535

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSPLAP00000025216	ENSPLAP00000001204	ENSPLAP00000025216	Cell division cycle 42.	Ras homolog gene family, member Gd.	0.595
CDC42	ENSPLAP00000025295	ENSPLAP00000001204	ENSPLAP00000025295	Cell division cycle 42.	Uncharacterized protein.	0.602
CDC42	LOC106941957	ENSPLAP00000001204	ENSPLAP00000020635	Cell division cycle 42.	Epithelial cell transforming 2.	0.803
CDC42	LOC106951125	ENSPLAP00000001204	ENSPLAP00000002512	Cell division cycle 42.	Uncharacterized protein.	0.854
CDC42	LOC106960410	ENSPLAP00000001204	ENSPLAP00000012095	Cell division cycle 42.	Ras homolog family member Gb.	0.597
CDC42	PLEKHG1	ENSPLAP00000001204	ENSPLAP00000001310	Cell division cycle 42.	Pleckstrin homology and RhoGEF domain containing G1.	0.559
ENSPLAP00000025216	CDC42	ENSPLAP00000025216	ENSPLAP00000001204	Ras homolog gene family, member Gd.	Cell division cycle 42.	0.595
ENSPLAP00000025216	ENSPLAP00000025295	ENSPLAP00000025216	ENSPLAP00000025295	Ras homolog gene family, member Gd.	Uncharacterized protein.	0.955
ENSPLAP00000025216	LOC106941957	ENSPLAP00000025216	ENSPLAP00000020635	Ras homolog gene family, member Gd.	Epithelial cell transforming 2.	0.599
ENSPLAP00000025216	LOC106951125	ENSPLAP00000025216	ENSPLAP00000002512	Ras homolog gene family, member Gd.	Uncharacterized protein.	0.509
ENSPLAP00000025216	LOC106960410	ENSPLAP00000025216	ENSPLAP00000012095	Ras homolog gene family, member Gd.	Ras homolog family member Gb.	0.897
ENSPLAP00000025216	LOC106964683	ENSPLAP00000025216	ENSPLAP00000021331	Ras homolog gene family, member Gd.	Cell division cycle 42.	0.595
ENSPLAP00000025216	PLEKHG1	ENSPLAP00000025216	ENSPLAP00000001310	Ras homolog gene family, member Gd.	Pleckstrin homology and RhoGEF domain containing G1.	0.540
ENSPLAP00000025295	CDC42	ENSPLAP00000025295	ENSPLAP00000001204	Uncharacterized protein.	Cell division cycle 42.	0.602
ENSPLAP00000025295	ENSPLAP00000025216	ENSPLAP00000025295	ENSPLAP00000025216	Uncharacterized protein.	Ras homolog gene family, member Gd.	0.955
ENSPLAP00000025295	LOC106941957	ENSPLAP00000025295	ENSPLAP00000020635	Uncharacterized protein.	Epithelial cell transforming 2.	0.599
ENSPLAP00000025295	LOC106951125	ENSPLAP00000025295	ENSPLAP00000002512	Uncharacterized protein.	Uncharacterized protein.	0.518
ENSPLAP00000025295	LOC106960410	ENSPLAP00000025295	ENSPLAP00000012095	Uncharacterized protein.	Ras homolog family member Gb.	0.893
ENSPLAP00000025295	LOC106964683	ENSPLAP00000025295	ENSPLAP00000021331	Uncharacterized protein.	Cell division cycle 42.	0.601
ENSPLAP00000025295	PLEKHG1	ENSPLAP00000025295	ENSPLAP00000001310	Uncharacterized protein.	Pleckstrin homology and RhoGEF domain containing G1.	0.540