Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
egr2Early growth response 2b. (446 aa)    
Predicted Functional Partners:
ENSPLAP00000018506
Early growth response 3.
  
0.987
ENSPLAP00000004359
NGFI-A binding protein 2 (EGR1 binding protein 2).
   
 0.965
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2).
   
 0.965
fosb
FBJ murine osteosarcoma viral oncogene homolog B.
   
 0.936
ENSPLAP00000000660
Uncharacterized protein.
  
 
 
0.908
egr1
Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.
   
 0.880
LOC106938759
V-fos FBJ murine osteosarcoma viral oncogene homolog Ab.
   
 0.849
snai2
Snail family zinc finger 2.
    
   0.836
nab1
NGFI-A binding protein 1a (EGR1 binding protein 1).
    
 0.823
sox10
SRY-box transcription factor 10.
    
 0.812
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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