Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spock3SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3. (395 aa)    
Predicted Functional Partners:
mmp15
Matrix metallopeptidase 15b.
    
 0.610
LOC106934757
Matrix metallopeptidase 14b (membrane-inserted).
    
 0.610
LOC106964102
TIMP metallopeptidase inhibitor 2a.
     
  0.586
LOC106936699
TIMP metallopeptidase inhibitor 2b.
     
  0.586
LOC106963518
SPARC-like 2.
   
  
 0.536
sparc
Secreted protein, acidic, cysteine-rich (osteonectin).
   
  
 0.536
LOC106951157
Growth hormone 1.
    
 0.523
LOC106957088
Somatolactin alpha.
    
 0.523
fam222a
Family with sequence similarity 222 member A.
      
 0.519
LOC106960655
Pep_M12B_propep domain-containing protein.
     
 0.468
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: medium (46%) [HD]