Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC106963382G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (563 aa)    
Predicted Functional Partners:
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.918
LOC106938860
Arrestin, beta 2a.
    
 0.891
LOC106941570
Arrestin, beta 1.
    
 0.891
LOC106959807
Chemokine (C-X-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.746
ENSPLAP00000028138
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
 0.746
ENSPLAP00000028193
Chemokine (C-X-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.746
LOC106949454
Chemokine (C-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.742
LOC106942431
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
 0.742
cxcr4
C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.
    
 0.742
ENSPLAP00000009585
Rhodopsin.
    
 0.740
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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