Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
camk2aCalcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (469 aa)    
Predicted Functional Partners:
LOC106963247
Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family.
    
 0.976
ENSPLAP00000010842
Calmodulin-like 4a.
    
 0.946
ENSPLAP00000028939
Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.
    
  0.933
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.929
ENSPLAP00000027506
Si:ch211-66k16.27.
    
  0.921
LOC106959955
Phosphoinositide phospholipase C.
   
 0.917
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.917
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.916
LOC106934571
Ryanodine receptor 2b (cardiac).
    
 0.913
LOC106960988
Uncharacterized protein.
    
 0.913
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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