STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
camk2aCalcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (469 aa)    
Predicted Functional Partners:
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 
 0.947
LOC106963247
Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family.
   
 0.944
LOC106936200
Calmodulin.
   
 0.944
LOC106954010
Calmodulin.
   
 0.944
calm2
Calmodulin 2.
   
 0.944
LOC106934571
Ryanodine receptor 2b (cardiac).
    
 0.914
LOC106960988
Uncharacterized protein.
    
 0.908
LOC106937578
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
  0.904
plcg2
Phosphoinositide phospholipase C.
    
  0.904
ENSPLAP00000018924
Phosphoinositide phospholipase C.
   
 
 0.901
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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