| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC106960733 | qtrt1 | ENSPLAP00000018419 | ENSPLAP00000015404 | Queuosine salvage protein; Involved in salvaging queuosine. | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] | 0.774 |
| LOC106960733 | qtrt2 | ENSPLAP00000018419 | ENSPLAP00000001443 | Queuosine salvage protein; Involved in salvaging queuosine. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.729 |
| dus1l | gart | ENSPLAP00000030346 | ENSPLAP00000001708 | Dihydrouridine synthase 1-like (S. cerevisiae). | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.492 |
| dus1l | pusl1 | ENSPLAP00000030346 | ENSPLAP00000002956 | Dihydrouridine synthase 1-like (S. cerevisiae). | tRNA pseudouridine synthase. | 0.644 |
| dus1l | qtrt2 | ENSPLAP00000030346 | ENSPLAP00000001443 | Dihydrouridine synthase 1-like (S. cerevisiae). | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.617 |
| dus1l | trmt5 | ENSPLAP00000030346 | ENSPLAP00000026433 | Dihydrouridine synthase 1-like (S. cerevisiae). | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.762 |
| dus1l | trmu | ENSPLAP00000030346 | ENSPLAP00000006301 | Dihydrouridine synthase 1-like (S. cerevisiae). | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase. | 0.741 |
| dus1l | wdr43 | ENSPLAP00000030346 | ENSPLAP00000001076 | Dihydrouridine synthase 1-like (S. cerevisiae). | WD repeat domain 43. | 0.766 |
| gart | dus1l | ENSPLAP00000001708 | ENSPLAP00000030346 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Dihydrouridine synthase 1-like (S. cerevisiae). | 0.492 |
| gart | pts | ENSPLAP00000001708 | ENSPLAP00000026223 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 6-pyruvoyl tetrahydrobiopterin synthase. | 0.403 |
| gart | qtrt1 | ENSPLAP00000001708 | ENSPLAP00000015404 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] | 0.625 |
| gart | qtrt2 | ENSPLAP00000001708 | ENSPLAP00000001443 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.625 |
| gart | trmu | ENSPLAP00000001708 | ENSPLAP00000006301 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase. | 0.486 |
| pts | gart | ENSPLAP00000026223 | ENSPLAP00000001708 | 6-pyruvoyl tetrahydrobiopterin synthase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.403 |
| pts | qtrt1 | ENSPLAP00000026223 | ENSPLAP00000015404 | 6-pyruvoyl tetrahydrobiopterin synthase. | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] | 0.614 |
| pts | qtrt2 | ENSPLAP00000026223 | ENSPLAP00000001443 | 6-pyruvoyl tetrahydrobiopterin synthase. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.640 |
| pusl1 | dus1l | ENSPLAP00000002956 | ENSPLAP00000030346 | tRNA pseudouridine synthase. | Dihydrouridine synthase 1-like (S. cerevisiae). | 0.644 |
| pusl1 | qtrt2 | ENSPLAP00000002956 | ENSPLAP00000001443 | tRNA pseudouridine synthase. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.601 |
| pusl1 | trmt5 | ENSPLAP00000002956 | ENSPLAP00000026433 | tRNA pseudouridine synthase. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.432 |
| pusl1 | trmu | ENSPLAP00000002956 | ENSPLAP00000006301 | tRNA pseudouridine synthase. | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase. | 0.549 |