Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPLAP00000001507Protein kinase domain-containing protein. (451 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.947
SRC
Tyrosine-protein kinase.
  
 
 
0.931
LOC106954618
Tyrosine-protein kinase.
  
 
 
0.931
sos2
Son of sevenless homolog 2 (Drosophila).
    
  0.928
LOC106952307
Epithelial membrane protein 1.
     
  0.900
LOC106963636
Kit ligand a.
    
 0.873
LOC106954316
Uncharacterized protein.
    
 0.806
pik3r3
Uncharacterized protein.
    
 0.806
LOC106941461
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
 0.806
LOC106938218
SH2 domain-containing protein.
    
 0.806
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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