ENSPLAP00000001507 protein (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSPLAP00000001507

Protein kinase domain-containing protein. (451 aa)

Predicted Functional Partners:

grb2

0.968

SRC

0.942

LOC106963636

0.939

LOC106937578

0.930

pdgfb

0.930

LOC106958605

0.929

fgf20

0.929

fgf16

0.929

LOC106946436

0.929

LOC106937852

0.929

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000001507	LOC106937578	ENSPLAP00000001507	ENSPLAP00000019727	Protein kinase domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.930
ENSPLAP00000001507	LOC106937852	ENSPLAP00000001507	ENSPLAP00000004140	Protein kinase domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.929
ENSPLAP00000001507	LOC106946436	ENSPLAP00000001507	ENSPLAP00000003718	Protein kinase domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.929
ENSPLAP00000001507	LOC106958605	ENSPLAP00000001507	ENSPLAP00000000027	Protein kinase domain-containing protein.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.929
ENSPLAP00000001507	LOC106963636	ENSPLAP00000001507	ENSPLAP00000014210	Protein kinase domain-containing protein.	Kit ligand a.	0.939
ENSPLAP00000001507	SRC	ENSPLAP00000001507	ENSPLAP00000014667	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.942
ENSPLAP00000001507	fgf16	ENSPLAP00000001507	ENSPLAP00000000359	Protein kinase domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.929
ENSPLAP00000001507	fgf20	ENSPLAP00000001507	ENSPLAP00000000143	Protein kinase domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.929
ENSPLAP00000001507	grb2	ENSPLAP00000001507	ENSPLAP00000012052	Protein kinase domain-containing protein.	Growth factor receptor-bound protein 2b.	0.968
ENSPLAP00000001507	pdgfb	ENSPLAP00000001507	ENSPLAP00000020496	Protein kinase domain-containing protein.	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	0.930
LOC106937578	ENSPLAP00000001507	ENSPLAP00000019727	ENSPLAP00000001507	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Protein kinase domain-containing protein.	0.930
LOC106937578	LOC106937852	ENSPLAP00000019727	ENSPLAP00000004140	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.437
LOC106937578	LOC106946436	ENSPLAP00000019727	ENSPLAP00000003718	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.437
LOC106937578	SRC	ENSPLAP00000019727	ENSPLAP00000014667	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Tyrosine-protein kinase.	0.527
LOC106937578	fgf16	ENSPLAP00000019727	ENSPLAP00000000359	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.468
LOC106937578	fgf20	ENSPLAP00000019727	ENSPLAP00000000143	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.468
LOC106937578	grb2	ENSPLAP00000019727	ENSPLAP00000012052	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Growth factor receptor-bound protein 2b.	0.903
LOC106937578	pdgfb	ENSPLAP00000019727	ENSPLAP00000020496	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	0.524
LOC106937852	ENSPLAP00000001507	ENSPLAP00000004140	ENSPLAP00000001507	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein kinase domain-containing protein.	0.929
LOC106937852	LOC106937578	ENSPLAP00000004140	ENSPLAP00000019727	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.437