csf1r protein (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

csf1r

Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1016 aa)

Predicted Functional Partners:

il34

0.996

LOC106963636

0.987

grb2

0.966

LOC106940123

0.961

LOC106939822

0.901

fgf23

0.833

ENSPLAP00000004479

0.816

vegfa

0.815

gdnf

0.811

pdgfb

0.811

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000004479	LOC106939822	ENSPLAP00000004479	ENSPLAP00000014744	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Colony stimulating factor 1 receptor, a.	0.816
ENSPLAP00000004479	csf1r	ENSPLAP00000004479	ENSPLAP00000001515	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.816
ENSPLAP00000004479	fgf23	ENSPLAP00000004479	ENSPLAP00000015175	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.412
LOC106939822	ENSPLAP00000004479	ENSPLAP00000014744	ENSPLAP00000004479	Colony stimulating factor 1 receptor, a.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.816
LOC106939822	LOC106940123	ENSPLAP00000014744	ENSPLAP00000005569	Colony stimulating factor 1 receptor, a.	Uncharacterized protein.	0.961
LOC106939822	LOC106963636	ENSPLAP00000014744	ENSPLAP00000014210	Colony stimulating factor 1 receptor, a.	Kit ligand a.	0.987
LOC106939822	csf1r	ENSPLAP00000014744	ENSPLAP00000001515	Colony stimulating factor 1 receptor, a.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.901
LOC106939822	fgf23	ENSPLAP00000014744	ENSPLAP00000015175	Colony stimulating factor 1 receptor, a.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.833
LOC106939822	gdnf	ENSPLAP00000014744	ENSPLAP00000017982	Colony stimulating factor 1 receptor, a.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.811
LOC106939822	grb2	ENSPLAP00000014744	ENSPLAP00000012052	Colony stimulating factor 1 receptor, a.	Growth factor receptor-bound protein 2b.	0.966
LOC106939822	il34	ENSPLAP00000014744	ENSPLAP00000026519	Colony stimulating factor 1 receptor, a.	Interleukin 34.	0.997
LOC106939822	pdgfb	ENSPLAP00000014744	ENSPLAP00000020496	Colony stimulating factor 1 receptor, a.	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	0.811
LOC106939822	vegfa	ENSPLAP00000014744	ENSPLAP00000008541	Colony stimulating factor 1 receptor, a.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.815
LOC106940123	LOC106939822	ENSPLAP00000005569	ENSPLAP00000014744	Uncharacterized protein.	Colony stimulating factor 1 receptor, a.	0.961
LOC106940123	LOC106963636	ENSPLAP00000005569	ENSPLAP00000014210	Uncharacterized protein.	Kit ligand a.	0.613
LOC106940123	csf1r	ENSPLAP00000005569	ENSPLAP00000001515	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.961
LOC106940123	il34	ENSPLAP00000005569	ENSPLAP00000026519	Uncharacterized protein.	Interleukin 34.	0.990
LOC106940123	vegfa	ENSPLAP00000005569	ENSPLAP00000008541	Uncharacterized protein.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.542
LOC106963636	LOC106939822	ENSPLAP00000014210	ENSPLAP00000014744	Kit ligand a.	Colony stimulating factor 1 receptor, a.	0.987
LOC106963636	LOC106940123	ENSPLAP00000014210	ENSPLAP00000005569	Kit ligand a.	Uncharacterized protein.	0.613