Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (926 aa)    
Predicted Functional Partners:
ENSPLAP00000022886
R-spondin 2.
   
 0.993
LOC106939840
R-spondin 3.
   
 0.992
znrf3
Zinc and ring finger 3.
    
 0.969
RNF43
Ring finger protein 43.
    
 0.946
LOC106946991
G_PROTEIN_RECEP_F1_2 domain-containing protein.
  
 
 
0.938
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
  
 
 
0.931
LOC106950533
Calcium homeostasis endoplasmic reticulum protein.
    
 0.820
ndp
Norrin cystine knot growth factor NDP.
    
 0.787
RSPO3
R-spondin 3.
   
 0.743
fzd6
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 
 0.743
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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