Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC106950551AMP-binding domain-containing protein. (701 aa)    
Predicted Functional Partners:
fasn
Coiled-coil domain containing 57.
    
 0.924
acox1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.834
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.762
acsl3
Uncharacterized protein.
  
 
0.752
LOC106962200
Acyl-CoA synthetase long chain family member 3b.
  
 
0.751
acsl4
Acyl-CoA synthetase long chain family member 4a.
  
 
0.749
hsdl2
Hydroxysteroid dehydrogenase like 2.
  
 0.745
rps27a
Ribosomal protein S27a.
    
  0.740
LOC106936237
Sterol carrier protein 2b.
  
 
 0.737
scp2
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.737
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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