Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPLAP00000001631CARD domain-containing protein. (126 aa)    
Predicted Functional Partners:
fancm
Uncharacterized protein.
    
 0.716
lin52
Lin-52 DREAM MuvB core complex component.
    
 0.527
lin54
Lin-54 DREAM MuvB core complex component.
    
 0.527
LOC106964595
Uncharacterized protein.
  
     0.487
lin9
Lin-9 DREAM MuvB core complex component.
    
 0.461
med14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.450
med23
Mediator complex subunit 23.
    
  0.448
kremen1
Kringle containing transmembrane protein 1.
    
  0.437
LOC106945155
Cortistatin.
    
  0.437
wscd2
WSC domain containing 2.
    
  0.437
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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