Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
limk2LIM domain kinase 2. (684 aa)    
Predicted Functional Partners:
LOC106949815
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 0.993
cfl2
Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.
   
 0.992
dstn
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.985
LOC106950198
Rho-associated, coiled-coil containing protein kinase 2a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
0.958
rock1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
0.958
ROCK2
Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
0.952
LOC106957248
LIM domain kinase 1a.
  
  
 
0.902
ENSPLAP00000014374
Protein kinase domain-containing protein.
  
  
 
0.901
PAK3
Non-specific serine/threonine protein kinase.
    
0.898
pak1
Non-specific serine/threonine protein kinase.
    
0.898
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.