ppargc1a protein (Poecilia latipinna) - STRING interaction network

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Score

ppargc1a

Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (781 aa)

Predicted Functional Partners:

esrra

0.997

sirt1

0.974

PPARA

0.966

PPARG

0.966

nrf1

0.959

bud31

0.940

crnkl1

0.939

xab2

0.935

cwc15

0.935

ppard

0.928

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PPARA	PPARG	ENSPLAP00000002432	ENSPLAP00000012995	Peroxisome proliferator-activated receptor alpha b.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.574
PPARA	nrf1	ENSPLAP00000002432	ENSPLAP00000030836	Peroxisome proliferator-activated receptor alpha b.	Nuclear respiratory factor 1.	0.440
PPARA	ppargc1a	ENSPLAP00000002432	ENSPLAP00000001710	Peroxisome proliferator-activated receptor alpha b.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.966
PPARA	sirt1	ENSPLAP00000002432	ENSPLAP00000005614	Peroxisome proliferator-activated receptor alpha b.	Sirtuin 1.	0.920
PPARG	PPARA	ENSPLAP00000012995	ENSPLAP00000002432	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Peroxisome proliferator-activated receptor alpha b.	0.574
PPARG	esrra	ENSPLAP00000012995	ENSPLAP00000024403	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Estrogen-related receptor alpha.	0.515
PPARG	nrf1	ENSPLAP00000012995	ENSPLAP00000030836	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Nuclear respiratory factor 1.	0.440
PPARG	ppard	ENSPLAP00000012995	ENSPLAP00000026022	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Peroxisome proliferator-activated receptor delta b.	0.945
PPARG	ppargc1a	ENSPLAP00000012995	ENSPLAP00000001710	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.966
PPARG	sirt1	ENSPLAP00000012995	ENSPLAP00000005614	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Sirtuin 1.	0.946
bud31	crnkl1	ENSPLAP00000028048	ENSPLAP00000005391	BUD31 homolog.	Crooked neck pre-mRNA splicing factor 1.	0.998
bud31	cwc15	ENSPLAP00000028048	ENSPLAP00000031057	BUD31 homolog.	CWC15 spliceosome associated protein homolog.	0.975
bud31	ppargc1a	ENSPLAP00000028048	ENSPLAP00000001710	BUD31 homolog.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.940
bud31	xab2	ENSPLAP00000028048	ENSPLAP00000030711	BUD31 homolog.	XPA binding protein 2.	0.998
crnkl1	bud31	ENSPLAP00000005391	ENSPLAP00000028048	Crooked neck pre-mRNA splicing factor 1.	BUD31 homolog.	0.998
crnkl1	cwc15	ENSPLAP00000005391	ENSPLAP00000031057	Crooked neck pre-mRNA splicing factor 1.	CWC15 spliceosome associated protein homolog.	0.958
crnkl1	ppargc1a	ENSPLAP00000005391	ENSPLAP00000001710	Crooked neck pre-mRNA splicing factor 1.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.939
crnkl1	xab2	ENSPLAP00000005391	ENSPLAP00000030711	Crooked neck pre-mRNA splicing factor 1.	XPA binding protein 2.	0.999
cwc15	bud31	ENSPLAP00000031057	ENSPLAP00000028048	CWC15 spliceosome associated protein homolog.	BUD31 homolog.	0.975
cwc15	crnkl1	ENSPLAP00000031057	ENSPLAP00000005391	CWC15 spliceosome associated protein homolog.	Crooked neck pre-mRNA splicing factor 1.	0.958