Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC106947310Fibrinogen alpha chain. (587 aa)    
Predicted Functional Partners:
fgb
Fibrinogen beta chain.
   
0.999
fgg
Fibrinogen gamma chain.
   
0.999
f2
Coagulation factor II (thrombin); Belongs to the peptidase S1 family.
   
 0.998
ENSPLAP00000006971
Alpha-2-HS-glycoprotein 2.
   
 0.986
serpinc1
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
   
 0.982
ENSPLAP00000006086
Uncharacterized protein.
   
 0.927
ENSPLAP00000006099
Uncharacterized protein.
   
 0.927
ENSPLAP00000022916
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.927
ENSPLAP00000023093
Kringle domain-containing protein.
   
 0.927
fam20c
FAM20C golgi associated secretory pathway kinase a.
    
  0.919
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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