Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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LOC106951159Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1708 aa)    
Predicted Functional Partners:
LOC106946905
Sodium channel, voltage-gated, type I, beta b.
    
 0.951
LOC106964728
Sodium channel, voltage-gated, type I, beta a.
    
 0.951
ENSPLAP00000020292
Uncharacterized protein.
   
 0.923
LOC106945684
Sodium channel, voltage-gated, type IV, beta a.
    
 0.886
ENSPLAP00000009347
Sodium channel, voltage-gated, type III, beta.
    
 0.802
ENSPLAP00000028051
Sodium channel, voltage-gated, type III, beta.
    
 0.802
ENSPLAP00000025908
Sodium channel, voltage-gated, type II, beta.
   
 0.766
IFT122
Intraflagellar transport 122.
   
 0.706
ENSPLAP00000016766
Uncharacterized protein.
  
 
0.701
ENSPLAP00000030764
Ion_trans domain-containing protein.
  
 
0.701
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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