STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106951159Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1708 aa)    
Predicted Functional Partners:
ENSPLAP00000020292
Uncharacterized protein.
   
 0.998
LOC106946905
Sodium channel, voltage-gated, type I, beta b.
    
 0.925
LOC106964728
Sodium channel, voltage-gated, type I, beta a.
    
 0.925
ENSPLAP00000025908
Sodium channel, voltage-gated, type II, beta.
   
 0.863
LOC106945684
Sodium channel, voltage-gated, type IV, beta a.
    
 0.799
LOC106937701
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.753
CACNG1
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.753
IFT122
Intraflagellar transport 122.
   
 0.751
wdr19
WD repeat domain 19.
    
 0.742
ift140
Intraflagellar transport 140 homolog (Chlamydomonas).
    
 0.737
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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