Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC106947306TIR domain-containing protein. (816 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.994
ENSPLAP00000005421
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
    
 0.982
LOC106946842
Toll-like receptor 1.
  
  
0.967
tollip
Toll interacting protein.
    
 0.955
RAC1
Rac family small GTPase 1.
   
 0.919
LOC106961773
Uncharacterized protein.
   
 0.919
LOC106961760
Uncharacterized protein.
   
 0.919
LOC106961755
Uncharacterized protein.
   
 0.919
LOC106947305
Toll-like receptor 2; Belongs to the Toll-like receptor family.
  
  
 
0.901
LOC106959996
Toll-like receptor 18.
     
 
0.900
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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