Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
slx4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1442 aa)    
Predicted Functional Partners:
LOC106956439
Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
   
 0.999
mus81
MUS81 structure-specific endonuclease subunit.
  
 0.998
eme1
Essential meiotic structure-specific endonuclease 1.
    
 0.998
eprs1
Uncharacterized protein.
  
 0.998
EPRS1
Glutamyl-prolyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.998
ercc1
Excision repair cross-complementation group 1.
   
 0.997
ercc4
Excision repair cross-complementation group 4.
  
 0.996
LOC106950461
HTH myb-type domain-containing protein.
  
 
 
 0.990
slx4ip
SLX4 interacting protein.
    
 
 0.987
terf2ip
BRCT domain-containing protein.
    
 
 0.985
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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