Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
LOC106940390Nuclear receptor interacting protein 2. (271 aa)    
Predicted Functional Partners:
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 
 0.804
sf3a2
Splicing factor 3a, subunit 2.
   
   0.762
LOC106937893
Proteasome 26S subunit, non-ATPase 4b.
   
 
 0.673
LOC106959157
Proteasome 26S subunit, non-ATPase 4a.
   
 
 0.673
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 
 0.670
rad23a
RAD23 homolog A, nucleotide excision repair protein a.
   
 
 0.670
psmd14
Proteasome 26S subunit, non-ATPase 14.
   
 
 0.648
mpnd
MPN domain containing.
   
 
 0.648
mysm1
Myb-like, SWIRM and MPN domains 1.
   
 
 0.648
dyrk4
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4.
    
 
 0.554
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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