Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
edarEctodysplasin A receptor. (536 aa)    
Predicted Functional Partners:
edaradd
EDAR-associated death domain.
    
 0.990
eda
Ectodysplasin A; Belongs to the tumor necrosis factor family.
     
 0.978
lef1
Lymphoid enhancer-binding factor 1.
      
 0.721
SLC24A5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.720
ENSPLAP00000020869
Uncharacterized protein.
      
 0.717
wnt6
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.715
runx2
Runt-related transcription factor.
      
 0.687
pcnx4
Pecanex 4.
      
 0.685
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
      
 0.683
LOC106948985
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
      
 0.651
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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