LOC106964810 protein (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC106964810

Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (918 aa)

Predicted Functional Partners:

map2k7

0.937

MAP3K12

0.924

mycbp2

0.841

casp9

0.570

dusp7

0.505

fbxo45

0.433

casp2

0.429

casp6

0.429

LOC106934608

0.429

casp3

0.429

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106934608	LOC106964810	ENSPLAP00000018701	ENSPLAP00000001945	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	0.429
LOC106934608	MAP3K12	ENSPLAP00000018701	ENSPLAP00000013869	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	0.429
LOC106934608	casp2	ENSPLAP00000018701	ENSPLAP00000002225	Uncharacterized protein.	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.612
LOC106934608	casp6	ENSPLAP00000018701	ENSPLAP00000008498	Uncharacterized protein.	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.540
LOC106934608	casp9	ENSPLAP00000018701	ENSPLAP00000005968	Uncharacterized protein.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.855
LOC106964810	LOC106934608	ENSPLAP00000001945	ENSPLAP00000018701	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Uncharacterized protein.	0.429
LOC106964810	MAP3K12	ENSPLAP00000001945	ENSPLAP00000013869	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	0.924
LOC106964810	casp2	ENSPLAP00000001945	ENSPLAP00000002225	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.429
LOC106964810	casp3	ENSPLAP00000001945	ENSPLAP00000022942	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.429
LOC106964810	casp6	ENSPLAP00000001945	ENSPLAP00000008498	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.429
LOC106964810	casp9	ENSPLAP00000001945	ENSPLAP00000005968	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.570
LOC106964810	dusp7	ENSPLAP00000001945	ENSPLAP00000025244	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.505
LOC106964810	fbxo45	ENSPLAP00000001945	ENSPLAP00000029133	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	F-box protein 45.	0.433
LOC106964810	map2k7	ENSPLAP00000001945	ENSPLAP00000026257	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Mitogen-activated protein kinase kinase 7.	0.937
LOC106964810	mycbp2	ENSPLAP00000001945	ENSPLAP00000016290	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	MYC binding protein 2.	0.841
MAP3K12	LOC106934608	ENSPLAP00000013869	ENSPLAP00000018701	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Uncharacterized protein.	0.429
MAP3K12	LOC106964810	ENSPLAP00000013869	ENSPLAP00000001945	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	0.924
MAP3K12	casp2	ENSPLAP00000013869	ENSPLAP00000002225	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.429
MAP3K12	casp3	ENSPLAP00000013869	ENSPLAP00000022942	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.429
MAP3K12	casp6	ENSPLAP00000013869	ENSPLAP00000008498	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.429