Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC106964810Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (918 aa)    
Predicted Functional Partners:
map2k7
Mitogen-activated protein kinase kinase 7.
    
0.952
map3k13
Mitogen-activated protein kinase kinase kinase.
  
  
 
0.902
MAP3K12
Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.
  
  
 
0.901
mycbp2
MYC binding protein 2.
    
 
 0.887
CDC25B
Cell division cycle 25B.
   
  
 0.532
fbxo45
F-box protein 45.
    
 
 0.521
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
      
 0.513
ENSPLAP00000030938
FRA10A associated CGG repeat 1.
    
   0.512
mapk8ip2
Mitogen-activated protein kinase 8 interacting protein 2.
    
 
 0.488
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 
 0.488
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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