Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC106955177BHLH domain-containing protein. (273 aa)    
Predicted Functional Partners:
nkx2-2
NK2 homeobox 2a.
   
 0.779
sox10
SRY-box transcription factor 10.
    
 
 0.732
LOC106960612
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
 
 0.712
nkx6-1
NK6 homeobox 1.
   
  
 0.682
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.639
elavl3
ELAV-like protein; Belongs to the RRM elav family.
   
  
 0.551
sp7
Sp7 transcription factor.
    
 
 0.543
mnx1
Motor neuron and pancreas homeobox 1.
    
 
 0.538
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase.
      
 0.537
fgf2
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 
 0.533
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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