Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sncaipSynuclein, alpha interacting protein. (890 aa)    
Predicted Functional Partners:
LOC106965224
Uncharacterized protein; Belongs to the synuclein family.
    
 0.995
ENSPLAP00000014644
zf-RING_14 domain-containing protein.
    
 0.974
ENSPLAP00000014649
RBR-type E3 ubiquitin transferase.
    
 0.974
ENSPLAP00000028744
Ubiquitin-like domain-containing protein.
    
 0.974
LOC106938609
Uncharacterized protein; Belongs to the synuclein family.
    
 0.909
LOC106948771
Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.
    
 0.889
sh3bp5l
SH3-binding domain protein 5-like, a.
    
 
 0.859
siah1
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 0.848
LOC106944291
Ubiquitin_5 domain-containing protein.
    
 
 0.836
LOC106938861
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 0.836
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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