close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sncaipSynuclein, alpha interacting protein. (890 aa)    
Predicted Functional Partners:
LOC106965224
Uncharacterized protein; Belongs to the synuclein family.
    
 0.969
ENSPLAP00000014644
zf-RING_14 domain-containing protein.
    
 0.929
ENSPLAP00000014649
RBR-type E3 ubiquitin transferase.
    
 0.929
ENSPLAP00000028744
Ubiquitin-like domain-containing protein.
    
 0.929
LOC106938609
Uncharacterized protein; Belongs to the synuclein family.
    
 0.890
LOC106948771
Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.
    
 0.834
ENSPLAP00000010842
Calmodulin-like 4a.
    
 0.675
ift81
Intraflagellar transport 81 homolog.
    
 0.670
LOC106938861
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 0.669
siah1
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 0.669
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: medium (42%) [HD]