Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ero1aEndoplasmic reticulum oxidoreductase alpha. (459 aa)    
Predicted Functional Partners:
p4hb
Protein disulfide-isomerase.
   
 0.984
pdia4
Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.
   
 0.981
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
 0.969
txndc5
Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.
   
 0.967
erp44
Endoplasmic reticulum protein 44.
    
 0.935
ero1b
Endoplasmic reticulum oxidoreductase beta.
  
  
 
0.901
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
  
 
 0.857
ENSPLAP00000003448
Thioredoxin domain-containing protein.
   
 0.856
ENSPLAP00000021304
annotation not available
   
 0.856
LOC106942385
Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.
   
 0.856
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: low (16%) [HD]