STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hrasHRas proto-oncogene, GTPase a. (189 aa)    
Predicted Functional Partners:
araf
A-Raf proto-oncogene, serine/threonine kinase.
  
 0.985
nf1
Neurofibromin 1b.
    
 0.981
sos2
Son of sevenless homolog 2 (Drosophila).
    
 0.979
braf
B-Raf proto-oncogene, serine/threonine kinase.
  
 0.978
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
   
 0.973
RASA2
RAS p21 protein activator 2.
    
 0.970
RASGRP2
RAS guanyl releasing protein 2.
    
 0.969
RASGRP1
RAS guanyl releasing protein 1.
    
 0.969
LOC106946558
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
   
 0.967
LOC106934590
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.967
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: low (40%) [HD]