STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1111 aa)    
Predicted Functional Partners:
LOC106963571
Uncharacterized protein.
    
 0.955
LOC106947790
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.942
itpr1
Inositol 1,4,5-trisphosphate receptor, type 1a.
    
 0.939
LOC106954508
G protein subunit alpha q.
    
 0.931
itpr2
Inositol 1,4,5-trisphosphate receptor, type 2.
    
 0.921
INPP5A
Inositol polyphosphate-5-phosphatase A.
   
 
 0.911
LOC106959359
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.909
ipmk
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.904
mtm1
Myotubularin 1.
     
 0.901
inpp1
Si:ch211-160o17.2.
     
 0.900
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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