STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
btkTyrosine-protein kinase. (637 aa)    
Predicted Functional Partners:
ENSPLAP00000015356
Lymphocyte cytosolic protein 2a.
   
 0.863
ENSPLAP00000020136
SH2 domain-containing protein.
   
 0.801
ENSPLAP00000008841
Uncharacterized protein.
   
 0.791
LOC106940006
GRB2 related adaptor protein 2a.
   
0.758
grb2
Growth factor receptor-bound protein 2b.
   
0.743
met
MET proto-oncogene, receptor tyrosine kinase.
    
 
0.709
LOC106949456
Macrophage stimulating 1 receptor a.
    
 
0.709
mst1r
Macrophage stimulating 1 receptor b.
    
 
0.709
LOC106961785
RUN and FYVE domain containing 1.
    
  0.708
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.706
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.