Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC106949950Si:ch73-71d17.2. (806 aa)    
Predicted Functional Partners:
mlh1
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
    
   0.857
LOC106944053
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1.
      
 0.680
zranb3
Zinc finger, RAN-binding domain containing 3.
      
 0.619
brca2
BRCA2 DNA repair associated.
      
 0.573
dna2
Uncharacterized protein.
      
 0.555
fbh1
F-box DNA helicase 1.
      
 0.544
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
      
 0.536
exo1
Exonuclease 1.
      
 0.527
fancd2
FA complementation group D2.
      
 0.524
ENSPLAP00000000036
Uncharacterized protein.
      
 0.518
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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