STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ndufs2Kirre like nephrin family adhesion molecule 1a. (820 aa)    
Predicted Functional Partners:
nphs1
NPHS1 adhesion molecule, nephrin.
   
0.962
nck1
Cytoplasmic protein.
    
 0.714
nck2
Cytoplasmic protein.
    
 0.714
LOC106961235
Tight junction protein 1a; Belongs to the MAGUK family.
    
 0.529
LOC106937846
Tight junction protein 1b; Belongs to the MAGUK family.
    
 0.529
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.516
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 
0.510
ENSPLAP00000007782
Corin, serine peptidase.
    
  0.509
LOC106949978
Si:ch211-221f10.2.
   
 0.499
abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5.
   
 0.499
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.