Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC106939465RAB5C, member RAS oncogene family. (220 aa)    
Predicted Functional Partners:
LOC106952935
RAB guanine nucleotide exchange factor (GEF) 1, like.
   
 0.992
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1.
   
 0.992
LOC106951453
Uncharacterized protein.
   
 0.992
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.982
eea1
Early endosome antigen 1.
    
 0.954
rbsn
Rabenosyn, RAB effector.
    
 0.941
vps18
VPS18 core subunit of CORVET and HOPS complexes.
    
 0.896
rabep1
Rabaptin, RAB GTPase binding effector protein 1.
    
 0.893
vps16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
    
 0.886
vps11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
 0.878
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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