poli protein (Poecilia latipinna) - STRING interaction network

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Predicted Interactions

gene neighborhood

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[Homology]

Score

poli

Polymerase (DNA directed) iota. (672 aa)

Predicted Functional Partners:

pcna

0.988

rev1

0.986

rev3l

0.973

rps27a

0.971

uba52

0.957

ENSPLAP00000015559

0.923

pold1

0.912

pole

0.902

tp53

0.898

rad18

0.890

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000015559	pcna	ENSPLAP00000015559	ENSPLAP00000001196	Ubiquitin-like domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.946
ENSPLAP00000015559	pold1	ENSPLAP00000015559	ENSPLAP00000011114	Ubiquitin-like domain-containing protein.	DNA polymerase.	0.691
ENSPLAP00000015559	pole	ENSPLAP00000015559	ENSPLAP00000002628	Ubiquitin-like domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.671
ENSPLAP00000015559	poli	ENSPLAP00000015559	ENSPLAP00000003503	Ubiquitin-like domain-containing protein.	Polymerase (DNA directed) iota.	0.923
ENSPLAP00000015559	rad18	ENSPLAP00000015559	ENSPLAP00000011560	Ubiquitin-like domain-containing protein.	RAD18 E3 ubiquitin protein ligase.	0.910
ENSPLAP00000015559	rev1	ENSPLAP00000015559	ENSPLAP00000030296	Ubiquitin-like domain-containing protein.	REV1 DNA directed polymerase.	0.922
ENSPLAP00000015559	rev3l	ENSPLAP00000015559	ENSPLAP00000000412	Ubiquitin-like domain-containing protein.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.667
ENSPLAP00000015559	rps27a	ENSPLAP00000015559	ENSPLAP00000025723	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.997
ENSPLAP00000015559	tp53	ENSPLAP00000015559	ENSPLAP00000022694	Ubiquitin-like domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.586
pcna	ENSPLAP00000015559	ENSPLAP00000001196	ENSPLAP00000015559	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin-like domain-containing protein.	0.946
pcna	pold1	ENSPLAP00000001196	ENSPLAP00000011114	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase.	0.999
pcna	pole	ENSPLAP00000001196	ENSPLAP00000002628	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.992
pcna	poli	ENSPLAP00000001196	ENSPLAP00000003503	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Polymerase (DNA directed) iota.	0.988
pcna	rad18	ENSPLAP00000001196	ENSPLAP00000011560	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	RAD18 E3 ubiquitin protein ligase.	0.996
pcna	rev1	ENSPLAP00000001196	ENSPLAP00000030296	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	REV1 DNA directed polymerase.	0.990
pcna	rev3l	ENSPLAP00000001196	ENSPLAP00000000412	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.985
pcna	rps27a	ENSPLAP00000001196	ENSPLAP00000025723	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ribosomal protein S27a.	0.981
pcna	tp53	ENSPLAP00000001196	ENSPLAP00000022694	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.736
pcna	uba52	ENSPLAP00000001196	ENSPLAP00000027495	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.966
pold1	ENSPLAP00000015559	ENSPLAP00000011114	ENSPLAP00000015559	DNA polymerase.	Ubiquitin-like domain-containing protein.	0.691