Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MARCHF6Membrane associated ring-CH-type finger 6. (915 aa)    
Predicted Functional Partners:
ube2g2
Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.945
sqle
Squalene epoxidase a.
    
 
 0.944
ube2j2
Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast).
    
 
 0.914
syvn1
Synovial apoptosis inhibitor 1, synoviolin.
    
 
 0.872
amfr
Autocrine motility factor receptor b.
    
 
 0.872
LOC106962768
C1q and TNF related 12.
    
 
 0.862
cnot2
CCR4-NOT transcription complex, subunit 2.
    
 
 0.798
LOC106946362
NOT2_3_5 domain-containing protein.
    
 
 0.798
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.766
ufd1
Ubiquitin recognition factor in ER associated degradation 1.
    
 
 0.762
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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