rfx3 protein (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

rfx3

Regulatory factor X, 3 (influences HLA class II expression). (760 aa)

Predicted Functional Partners:

chek2

0.879

atr

0.857

rfxap

0.808

rfxank

0.753

ankra2

0.714

ENSPLAP00000017372

0.674

LOC106965124

0.623

tonsl

0.611

LOC106959930

0.564

dclk1

0.564

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000017372	rfx3	ENSPLAP00000017372	ENSPLAP00000003604	Fork-head domain-containing protein.	Regulatory factor X, 3 (influences HLA class II expression).	0.674
LOC106959930	chek2	ENSPLAP00000001869	ENSPLAP00000014464	Doublecortin-like kinase 1b.	Checkpoint kinase 2.	0.772
LOC106959930	dclk1	ENSPLAP00000001869	ENSPLAP00000030100	Doublecortin-like kinase 1b.	Doublecortin-like kinase 1a.	0.629
LOC106959930	rfx3	ENSPLAP00000001869	ENSPLAP00000003604	Doublecortin-like kinase 1b.	Regulatory factor X, 3 (influences HLA class II expression).	0.564
LOC106965124	rfx3	ENSPLAP00000010781	ENSPLAP00000003604	Forkhead box J1b.	Regulatory factor X, 3 (influences HLA class II expression).	0.623
ankra2	rfx3	ENSPLAP00000004857	ENSPLAP00000003604	Ankyrin repeat, family A (RFXANK-like), 2.	Regulatory factor X, 3 (influences HLA class II expression).	0.714
ankra2	rfxap	ENSPLAP00000004857	ENSPLAP00000030093	Ankyrin repeat, family A (RFXANK-like), 2.	Regulatory factor X-associated protein.	0.922
ankra2	tonsl	ENSPLAP00000004857	ENSPLAP00000012476	Ankyrin repeat, family A (RFXANK-like), 2.	Tonsoku-like, DNA repair protein.	0.476
atr	chek2	ENSPLAP00000006227	ENSPLAP00000014464	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Checkpoint kinase 2.	0.997
atr	rfx3	ENSPLAP00000006227	ENSPLAP00000003604	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Regulatory factor X, 3 (influences HLA class II expression).	0.857
chek2	LOC106959930	ENSPLAP00000014464	ENSPLAP00000001869	Checkpoint kinase 2.	Doublecortin-like kinase 1b.	0.772
chek2	atr	ENSPLAP00000014464	ENSPLAP00000006227	Checkpoint kinase 2.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.997
chek2	dclk1	ENSPLAP00000014464	ENSPLAP00000030100	Checkpoint kinase 2.	Doublecortin-like kinase 1a.	0.772
chek2	rfx3	ENSPLAP00000014464	ENSPLAP00000003604	Checkpoint kinase 2.	Regulatory factor X, 3 (influences HLA class II expression).	0.879
dclk1	LOC106959930	ENSPLAP00000030100	ENSPLAP00000001869	Doublecortin-like kinase 1a.	Doublecortin-like kinase 1b.	0.629
dclk1	chek2	ENSPLAP00000030100	ENSPLAP00000014464	Doublecortin-like kinase 1a.	Checkpoint kinase 2.	0.772
dclk1	rfx3	ENSPLAP00000030100	ENSPLAP00000003604	Doublecortin-like kinase 1a.	Regulatory factor X, 3 (influences HLA class II expression).	0.564
rfx3	ENSPLAP00000017372	ENSPLAP00000003604	ENSPLAP00000017372	Regulatory factor X, 3 (influences HLA class II expression).	Fork-head domain-containing protein.	0.674
rfx3	LOC106959930	ENSPLAP00000003604	ENSPLAP00000001869	Regulatory factor X, 3 (influences HLA class II expression).	Doublecortin-like kinase 1b.	0.564
rfx3	LOC106965124	ENSPLAP00000003604	ENSPLAP00000010781	Regulatory factor X, 3 (influences HLA class II expression).	Forkhead box J1b.	0.623