STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aregAmphiregulin. (214 aa)    
Predicted Functional Partners:
egfr
Receptor protein-tyrosine kinase.
     
 0.942
LOC106934486
Receptor protein-tyrosine kinase.
     
 0.916
erbb3
Protein kinase domain-containing protein.
     
 0.875
erbb2
Receptor protein-tyrosine kinase.
     
 0.875
LOC106955349
Erb-b2 receptor tyrosine kinase 3b.
     
 0.875
LOC106956630
Receptor protein-tyrosine kinase.
     
 0.727
erbb4
Receptor protein-tyrosine kinase.
     
 0.689
fam83h
FAM83 domain-containing protein.
  
     0.459
LOC106963108
Si:ch211-168f7.5.
  
     0.427
LOC106947988
Uncharacterized protein.
  
     0.423
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.