Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sema5aSema domain-containing protein. (1078 aa)    
Predicted Functional Partners:
nrp1
Neuropilin; Belongs to the neuropilin family.
    
 0.730
ENSPLAP00000003369
Uncharacterized protein.
    
 0.721
plxnb1
Plexin b1b.
    
 0.721
ENSPLAP00000021228
Sema domain-containing protein.
    
 0.721
LOC106947660
Plexin b1a.
    
 0.721
plxnb2
Plexin b2b.
    
 0.670
LOC106953105
Plexin b2a.
    
 0.670
neil1
Nei-like DNA glycosylase 1.
      
 0.639
asns
Asparagine synthetase [glutamine-hydrolyzing].
      
 0.638
met
MET proto-oncogene, receptor tyrosine kinase.
   
 0.593
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.