Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dmtf1Cyclin D binding myb-like transcription factor 1. (665 aa)    
Predicted Functional Partners:
ccdc59
Coiled-coil domain containing 59.
     
  0.863
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.
   
 
 0.853
LOC106953350
Transcription initiation factor TFIID subunit.
    
 
 0.816
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.789
polr1e
RNA polymerase I subunit E.
    
 0.784
cd3eap
CD3e molecule, epsilon associated protein.
    
  0.767
gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
    
   0.746
LOC106943900
RNA polymerase I and III subunit C.
    
  0.745
polr1c
RNA polymerase I and III subunit C.
    
  0.745
rundc3b
RUN domain containing 3b.
      
 0.711
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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