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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPLAP00000003791Uncharacterized protein. (413 aa)    
Predicted Functional Partners:
LOC106956532
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3.
    
 
 0.738
wdr76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
    
 
 0.680
LOC106939034
Zgc:92313; Belongs to the peptidase S1 family.
      
 0.679
proc
Uncharacterized protein.
      
 0.679
cask
Uncharacterized protein; Belongs to the MAGUK family.
    
 0.616
LOC106956946
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
    
 0.616
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.597
LOC106951322
Guanylate cyclase.
    
 
 0.586
LOC106961585
Guanylate cyclase.
    
 
 0.586
rasl10a
RAS-like, family 10, member A.
    
 0.581
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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