Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pxkPX domain containing serine/threonine kinase. (559 aa)    
Predicted Functional Partners:
rps6kc1
Ribosomal protein S6 kinase polypeptide 1.
    
 0.731
snx21
Sorting nexin family member 21.
      
 0.685
sh3pxd2b
SH3 and PX domains 2B.
      
 0.681
rubcn
Rubicon autophagy regulator.
    
 
 0.574
fam219b
Family with sequence similarity 219 member B.
      
 0.506
mnat1
MNAT1 component of CDK activating kinase.
      
 0.497
rps6kl1
Ribosomal protein S6 kinase-like 1.
    
 0.452
cish
Uncharacterized protein.
     
 0.425
LOC106947163
NAD kinase b.
      
 0.419
nadk
NAD kinase a.
      
 0.419
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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